PONENTES

Biosketch
Andrea Guzzetta is Full Professor at the University of Pisa, Italy. He is Head of the Unit of Child Neurorehabilitation and Director of the Department of Developmental Neuroscience at the Stella Maris Scientific Institute in Pisa. He is also head of the Stella Maris Infant Lab for Early-intervention (SMILE), since its birth in 2022. He is Senior Tutor of the General Movements Trust since 2009.
Prof. Guzzetta main research has focused on the characterization of early abnormalities of neurodevelopment and their effect on the development of different functions and the underlying neuroplastic mechanisms, with the final aim
to improve early intervention paradigms and outcomes. In his research career he has provided some significant
contribution to a number of research questions in the area, thanks to his compound training experiences in some of
the most productive European centres in the field, including the Hammersmith Hospital and the Visual Development
Unit in London (Great Britain) and the Department of Child Neurology in Tuebingen (Germany).
Work experience
Current
Dates 02/05/2022 - Today
Position held Full Professor
@ University of Pisa – Department of Clinical and Experimental Medicine
Dates 01/09/2022 – Today
Position held Director of the Department of Developmental Neuroscience
@ Stella Maris Scientific Institute, Pisa
Dates 01/11/2021 – Today
Position held Clinical Director of the Unit of Child Neuropsychiatry and Neurorehabilitation
@ Stella Maris Scientific Institute, Pisa
Dates 01/01/2011 - Today
Position held Director of the Stella Maris Infant Lab for Early-intervention (SMILE)
@ Stella Maris Scientific Institute, Pisa
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Dates 01/03/2009 - Today
Position held Senior Tutor of the General Movements Assessment
@ General Movements Trust
Past
Dates 18/12/2016 – 01/05/2022
Position held Associate Professor of Child Neurology and Psychiatry
@ University of Pisa – Department of Clinical and Experimental Medicine
Dates 01/01/2019 – 01/11/2021
Position held Director of the UOS Unità per le Disabilità Gravi dell’Età Evolutiva
@ Fondazione Stella Maris, Pisa, Italy
Dates 18/12/2013 – 17/12/2016
Position held Assistant Professor of Child Neurology and Psychiatry
@ University of Pisa – Department of Clinical and Experimental Medicine
Dates 01/07/2009 - 10/12/2010
Position held Senior Research Fellow
@ University of Queensland, Brisbane, Australia
Dates 01/04/2007 - 30/06/2009
Position held Consultant neurologist at the NICU, Pisa University Hospital
Researcher at the MRI Lab
Researcher at the Neurology Section
@ Fondazione Stella Maris, Pisa, Italy
Education and training
Dates 01/01/2001 - 31/12/2004
Title of qualification awarded PhD in Basic and Developmental Neuroscience Principal subjects Development of the human nervous system after early brain damage: maturation and integration of motor and visuo-perceptual functions
Organisation University of Pisa Level of international
classification
ISCED 6
Dates 01/06/2004 - 28/02/2005
Type Research stage
Principal subjects Pediatric functional MRI
Organisation Dept. of Child Neurology, University Hospital of Tuebingen, Germany
Advisors: Prof. Ingeborg Krageloh-Mann; Prof. Martin Staudt
Dates 01/01/1997 - 24/10/2001
Title of qualification awarded First Class Honours specialization in Child Neurology and Psychiatry Principal subjects General Movements as a prognostic tool for the early assessment of congenital arterial stroke Organisation University of Pisa Level of international
classification
ISCED 6
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Dates 01/10/1999 - 30/05/2000
Type Research stage
Principal subjects Neonatal Neurology
Organisation Paediatrics Hammersmith Hospital Imperial College, London, UK
Advisors: Prof. Lilly Dubowitz; Prof. Eugenio Mercuri; Prof. Frances Cowan; Prof. Mary Rutherford
Dates 01/10/1999 - 28/02/2000
Type Research stage
Principal subjects Pediatric Neuro-ophthalmology
Organisation Visual Development Unit, London, Department of Psychology, University College, London, UK
Advisors: Prof. Janette Atkinson; Prof. Oliver Braddick
Dates 10/10/1989 - 10/04/1996
Title of qualification awarded First Class Honours degree in Medicine and Surgery
Thesis title Congenital hypothyroidism: correlation between hormonal indexes at birth and neurodevelopmental outcome
Organisation University of Rome “La Sapienza” Level of international classification
ISCED 5
International Awards
2012 Heinz Prechtl Award for Developmental Neurology
Main Funded Grants
Source Fondation Paralyse Cerebral
Grant Title ENSEMBLE - European Newborn Study: Early Markers for a Better LifE Starting year (duration in months) 2022 (60)
Amount funded (euro) 1.4M
Role Principal Investigator (N.B. The project has 3 PIs)
Source EU, HORIZON 2020
Grant Title BORNTOGETTHERE-Implementazione della diagnosi e dell’intervento precoce nel neonato a rischio neurologico Starting year (duration in months)
2019 (48)
Amount funded (euro) 3.7M
Role Principal Investigator
Source Fondation Paralyse Cerebral
Grant Title Functional, neuroplastic and biomechanical changes induced by early Hand and Arm Bimanual Intensive
Therapy Including Lower Extremities (HABIT-ILE) in pre-school children with uni-and-bilateral cerebral
palsy: a European project
Starting year (duration in months) 2018 (48)
Amount funded (euro) 1.0M
Role Co-Investigator, Head of WP
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Source Cerebral Palsy Alliance (AUS)
Grant Title VISIBLE: Vision Intervention for Seeing Impaired Babies through Learning and Enrichment.
Starting year (duration in months) 2018 (24)
Amount funded (euro) 0.2M
Role Principal Investigator
Source FAS Regione Toscana
Grant Title IMAGACTMED – Universal Accessibiity Systems to the Health System: instruction to patients through 3D
representations of the action.
Starting year (duration in months) 2017 (24)
Amount funded (euro) 1.0M
Role Co-Investigator, Head of WP
Source Horizon2020: Marie Sklodowska-Curie Actions - Innovative Training Networks (MSCA-ITN)
Grant Title Brainview - Integrated view on disruptions of early brain development
Starting year (duration in months) 2014 (36)
Amount funded (euro) 3.8M
Role Co-Tutor
Source FONDAZIONE MARIANI (Italy)
Grant Title R-15-96 - INEED (Italian Network for Early detection and Early intervention in Developmental disabilities):
Alliance for best practice in early detection of cerebral palsy.
Starting year (duration in months) 2014 (24)
Amount funded (euro) 38K
Role Principal Investigator
Source Fondation Jerome Lejeune
Grant Title Mapping cerebral circuits in Down syndrome
Starting year (duration in months) 2011 (30)
Amount funded (euro) 21k
Role Co-investigator, Head of WP
Source R-11-86_FONDAZIONE MARIANI (Italy)
Grant Title The effect of infant action observation training on the early development of hand reaching and grasping in healthy
infants and in infants with asymmetrical brain damage.
Starting year (duration in months)
2011 (40)
Amount funded (euro) 150k
Role Principal Investigator
Source GR-2008-1143201 Ministero della Salute (Italy)
Grant Title Non-invasive tools for early detection of Autism Spectrum Disorders
Starting year (duration in months)
2011 (36)
Amount funded (euro) 1.06M
Role Co-investigator, Head of WP
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Source DP110104292 Australia Research Council (Australia)
Grant Title Effect of Infant Hand Observation Training on the Early Development of Hand Reaching and Grasping in Healthy
Infants and those with Early Brain Damage
Starting year (duration in months)
2011 (24)
Amount funded (euro) 280K
Role Co-investigator
NOTE He has participated to other 17 projects as collaborator for a total of about 3.35M
Track record in summary
Source Google Scholar 05.07.2023
Total publications H index i10-index
Total citations 268 55 134 9307
10 Selected Scientific Publications
Novak I et al. Early, accurate diagnosis and early intervention in cerebral palsy: advances in diagnosis and treatment.
JAMA pediatrics 171 (9), 897-907
Einspieler C et al. Cerebral Palsy: Early Markers of Clinical Phenotype and Functional Outcome.
J Clin Med. 2019 Oct 4;8(10):1616. doi: 10.3390/jcm8101616.
Baranello G et al. Visual Function Classification System for children with cerebral palsy: development and
validation.
Dev Med Child Neurol. 2020 Jan;62(1):104-110.
Pannek K et al. Assessment of the structural brain network reveals altered connectivity in children with unilateral cerebral palsy due to periventricular white matter lesions.
Neuroimage Clin. 2014 Jun 4;5:84-92.
Tinelli F et al. Greater sparing of visual search abilities in children after congenital rather than acquired focal brain damage.
Neurorehabil Neural Repair. 2011;25(8):721-8.
Guzzetta A et al. Plasticity of the visual system after early brain damage.
Dev Med Child Neurol. 2010;52(10):891-900
Guzzetta A et al. Hand movements at 3 months predict later hemiplegia in term infants with neonatal cerebral infaction.
Dev Med Child Neurol. 2010 Aug;52(8):767-72.
Guzzetta A et al. Massage accelerates brain development and the maturation of visual function.
J Neurosci. 2009 May 6;29(18):6042-51.
Morrone MC et al. Inversion of perceived direction of motion caused by spatial undersampling in two
children with periventricular leukomalacia.
J Cogn Neurosci. 2008;20(6):1094- 106.
Eyre JA et al. Is hemiplegic cerebral palsy equivalent to amblyopia of the corticospinal system?
Ann Neurol 2007;62(5):493-503.
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International Conferences (>2010)
(Invited Lectures only)
2022 Sykes Symposium - Early Detection and Treatment for Infant and Children With or At-High-Risk of CP
Los Angeles, California (USA) – 22-23 April 2022
Lecture “Effects of early brain damage on the development of different functions and the underlying neuroplastic
mechanisms, with the final aim to improve early intervention paradigms and outcomes”.
1st Joint Conference Ukrainian Academy of Childhood Disability and European Academy of Childhood Disability
Kiev, Ukraine – 16-18 September 2021
Lecture “What is the best model of early intervention fro infants at risk of developmental delay?”.
62nd ESPR Annual Meeting – 11th International Congress UENPS – 5th International Congress EFCNI
Athens, Greece (online) – 14-18 September 2021
Lecture “Early intervention”.
Early detection and intervention in neurodevelopmental disorders. Internatioinal Virtual Symposium.
Copenhagen, Denmark (online) – 7-9 June 2021
Lecture “Magnetic resonance imaging and prediction of function in children with cerebral palsy”.
International AusCP-CTN Hot Topics
Brisbane, Australia (online) – 3-5 March 2021
Lecture “Update on the VISIBLE study for Seeing-Impaired Infants”.
23rd Biennial Conference of the Israeli Association for Child Development and Rehabilitation
Jerusalem, Israel (online) – 2-3 March 2021
Lecture “The marvelous 12 months: how the brain shapes itself for a life of relationships”.
32nd european Academy Of Childhood Disability Annual Meeting 2020
Poznan, Poland (online) – 25-28 November 2020
Lecture “The marvelous 12 months: how the brain shapes itself for a life of relationships”.
Miedzynarodowa konferencja naukowa - Wczesne wspomaganie rozwoju dziecka
Lodz, Poland – 6-7 December 2019
Lecture “How understanding adaptive early neuroplasticity can lead to better early intervention”.
I Congreso Internacional De Fisioterapia De Castilla – La Mancha Toledo, Spain – 25-27 October 2019
Lecture “Intervencion muy temprana en lactantes con dano cerebral: de la neurociencia a la evidencia clinica”.
Developmental changes in paediatric neurodisability: from concepts to diagnostics and therapy
Groeningen, The Netherlands – 20-22 June 2019
Lecture “Plasticité cérébrale et pathologies neurologiques néonatales/Cerebral plasticity and neonatal
neurologic diseases”.
47th Conference of SENP – Société Européenne de Neuropédiatrie
Paris, France – 22-23 March 2019
Lecture “Cerebral visual impairment - concequences for navigation through daily life.”.
Kids Rehab Conference. Australasian CP Clinical Trials Network (CRE Topics).
Brisbane, Australia – 06-10 March 2019
Lecture “Update of early detection of cerebral palsy and differential diagnosis with the general movement
assessment.”
From Risk to Chance: Advances in Neonatal Neurodevelopment
Tel Aviv, Israel – 18-19 December 2018
Lecture “Early neuroplasticity and Implications for Nedurorehabilitation”
Lecture “Activity and Interactivity: two sides of the same coin in very early intervention
Vth anual meeting of Lithuanian Academy of Childhood Disability
Kaunas, Lithuania – 30 November 2018
Lecture “Cerebral visual impairment in children”
Hot Topics in Cerebral Palsy Research Forum
Sydney, Australia – 5 November 2018
Lecture “The VISIBLE program: a new model of early intervention in infants with cerebral visual impairment”
Joint International Workshop UNDERSTANDING AND PROMOTING CHANGE FROM EARLY TO COMPLEX
SKILLS IN TYPICAL AND ATYPICAL DEVELOPMENT: A CROSS-POPULATION APPROACH
Bologna, Italy – 10-11 October 2018
Lecture “From early neuroplasticity to early intervention: The model of neonatal brain damage”
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The 1st Congress of the Global Children Healthcare Network & Cerebral Palsy Alliance
Changsha City, China – 15 September 2018
Lecture “Early detection of cerebral palsy”
Rehabilitation Symposium 2018
Zurich, Swiss – 13 September 2018
Lecture “Brain Plasticity and opportunities for early assessment and intervention in infants with early brain injury”
Australasian Cerebral Palsy Clinical Trials Network (AusCP-CTN)
Centre for Research Excellence (CRE) Hot Topics in Cerebral Palsy Research Forum
Brisbane, Australia – 9-10 November 2017
Lecture n.1 “New opportunities for Early intervention in infants with early brain injury”
Lecture n.2 “Early Intervention for infants with Cerebral Visual Impairment”
Lecture n.3 “Early detection General Movements update”
International School of Neuroscience “sir John Eccles” – Workshop 2017
From activity to interactivity: harnessing early adaptive plasticity for intervention in atypical development
Erice, Sicily, Italy – 17 October 2017
Lecture “Activity and interactivity in the early rehabilitation of newborns and infants with brain damage”
European Congress of Magnetic Resonance in Neuropediatrics 14th Meeting
Tübingen, Germany – 8-10 June 2017
Lecture “Reorganization in the visual domain”
CPRN annual meeting 2017
Oslo, Norway – 7 June 2017
Lecture “Early detection of cerebral palsy”
29th EACD Conference 2017
Amsterdam, The Netherlands - 17-20 May 2017
Keynote “From activity to interactivity: finding the active ingredient of very early intervention”
Melbourne University, Pediatric Educational Seminar
Melbourne, Australia – 16 March 2017
Lecture “Early detection and intervention for infants at high-risk of development impairments”
Belgian National Symposium of CP centres 2017
Bruxelles, Belgium – 27 January 2017
Lecture “Neuroplasticity of the young brain: implications for early intervention”
21th Conference of the Association for Child Development and Rehabilitation
Jerusalem, Israel – 8-10 November 2016
Lecture “Impairment of Visual Functions in Infants with Brain Damage: From Early Detection to Early Intervention”
International Summit - Early Intervention State of the Science
Stokholm, Sweden – 31 May 2016
Lecture “State of the Science on Vision Interventions and Future Directions”
8th Biennial Conference of the Australasian Academy of Cerebral Palsy and Developmental Medicine
Adelaide, Australia – 30 March -2 April 2016
Lecture “Behavioural assessment of visual functions in infants with brain lesions”
Early intervention: the power of parenting and practice - early intervention in the light of the ICF-CY
Groningen, the Netherlands - 7-9 April 2016
Lecture “Brain mirror properties in infancy and implications for early neurorehabilitation”
Nationwide Children's Hospital - Neonatal Grand Rounds Presentation
Columbus, Ohio, USA – 5 August 2015
Lecture “Brain plasticity following congenital lesions: implications for early neurorehabilitation”
International Conference of the European Academy of Childhood Disability
Copenhagen, Denmark – 27-30 May 2015
Lecture “Can we make use of critical periods for intervention in children with early brain damage?”
International Conference Non-Invasive tools for early detection of autism spectrum disorder
Rome, Italy – 16-17 October 2014
Lecture “Infant motor behaviour and ASD”
International Early Detection and Early Neurorehabilitation in CP Summit.
Vienna, Austria – 1-2 July 2014
Lecture “Vision in Cerebral Palsy”
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Mastery of manual skills: recent insights into typical and atypical development of manual ability
Groeningen, The Nederlands – 15-17 May 2014
Lecture “Intervention in children with unilateral spastic cerebral palsy: the effect of action-observation training.”
7th Biennial Conference of the Australasian Academy of Cerebral Palsy and Developmental Medicine
Cypress Lakes Resort, Hunter Valley - 11-14 March 2014
Lecture “Early Intervention. Working with infants at risk of Cerebral Palsy and their parents”
4th International CerebralPalsy Conference
Pisa, Italy - 10-13 October 2012
Lecture “Neural plasticity and early intervention in CP infants”
16th World Congress of the International Organization of Psychophysiology
Pisa, Italy – 13-17 September 2012
Invited Lecture “Brain plasticity and early intervention in preterm infants”
6th Biennal Conference of the Australasian Academy of Childhood Disability
Brisbane, Australia – 30 May – 2 June 2012
Lecture “Action Observation training: a new window on the brain for rehabilitation of early brain injury”
Mastery of manual skills: recent insights into typical and atypical development of manual ability
Groeningen, The Nederlands – 19-21 April 2012
Lecture “Plasticity of the visual system after early brain damage”
18th Mediterranean Meeting of Child Neurology in conjunction with the 5th Fred J. Epstein International
Symposium on New Horizons in Pediatric Neurology, Neurosurgery and Neurofibromatosis
Dead Sea, Israel – 18-22 March 2012
Lecture “Neuroplasticity following perinatal brain damage: insights on very early intervention”
Journées d’etude annuelles du CDI
Paris, France – 12-13 December 2011
Lecture “Plasticité cérébrale du système sensori-moteur après lésion cérébrale précoce : cas particulier des
membres supérieurs”
Queensland Healthy Hearing Symposium 2010
SurfAir Marcoola Beach, Sunshine Coast QLD, Australia – 1-3 September 2010
Lecture “Age-Related Plasticity in the auditory system”
5th Biennial Conference of the Australasian Academy of Cerebral Palsy & Developmental Medicine,
Christchurch, New Zealand – 3-6 March 2010
Lecture “Visual function in children with brain damage and cerebral palsy what’s different about the young brain.”
Personal skills and competences
Mother tongue(s) Italian
Self-assessment Understanding Speaking Writing
European level (*) Listening Reading Spoken interaction Spoken production
English C2 Proficient user C2 Proficient user C2 Proficient user C2 Proficient user C2 Proficient user
French B2 Independent user B2 Independent user A2 Basic user A2 Basic user A1 Basic user

Doctor en Fisioterapia por la Universidad de Salamanca (julio de 2017).
Graduado en Fisioterapia E.U. de Enfermería y Fisioterapia de la Universidad de Salamanca (2011-2012).
Máster oficial en “Tratamiento de soporte y cuidados paliativos en el paciente oncológico“. Universidad de Salamanca (2010-2011).
Diplomado en Fisioterapia por la E.U. de Enfermería y Fisioterapia de la Universidad de Salamanca (1999-2002).
Título de Experto Universitario en Metodología de la Investigación en Ciencias de la Salud. Universidad de Salamanca (2013).
Título Experto en Ejercicio Terapéutico Universidad de Málaga (2022).
Creador y coordinador (junto a Miguel Ángel Galán Martín) de la Unidad de Estrategias de Afrontamiento activo para el tratamiento del dolor crónico en Atención Primaria de Sacyl Valladolid, primera unidad de dolor en Atención Primaria de nuestro país, desde septiembre de 2018 hasta la actualidad.
Profesor Universidad Europea Miguel de Cervantes de Valladolid (desde curso 2017/2018 hasta la actualidad).
Profesor Asociado Clínico Universidad de Valladolid -Profesor “Máster de Terapia Manual”, título propio Universidad de Valladolid (desde curso 2010-2011 hasta 2020).
Profesor Máster de Terapia Manual y Osteopatía de la EU de la ONCE Madrid.
Profesor del curso de posgrado “Dolor y Neurociencias, nuevo abordaje fisioterapéutico” 30 horas de duración (más de 30 ediciones).

Otros méritos:

Investigador principal de varios proyectos financiados relacionados con Neurociencia, discapacidad y calidad de vida.
Coordinador del Proyecto Europeo Investigo en la Sanidad de Castilla y León (SACYL).
Publicación de varios artículos científicos en revistas de alto impacto.
Miembro de la Sociedad Española de Fisioterapia y Dolor (SEFID).
Socio fundador de la Sociedad de Estrategias de Afrontamiento Activo para el dolor crónico.
Miembro del grupo de trabajo de protocolos de fisioterapia de SACYL.
Miembro del grupo de trabajo de la Guía de dolor crónico primario del Ministerio de Sanidad de España.

Premios recibidos:

Premio Sedap-Ferrer a la mejor experiencia innovadora en Atención Primaria 2018. Junio de 2018, Valladolid.
Premio Fisioterapeuta del año 2019 (Exaquo Miguel Ángel Galán QEPD) V Premios Euskadi. Diciembre de 2019, San Sebastián.
Premio Mejor artículo Investigación en Atención Primaria Valladolid Octubre 2019.
Premio Especial Hospitalidad. XIV Premios San Juan de Dios, Universidad de Comillas. Abril 2023 Madrid
Premios Cocemfe Castilla y León. Entidad Amable: Unidad de Estrategias de Afrontamiento activo para el dolor crónico de Sacyl. Palencia, diciembre de 2023.
Premio Excelencia en Fisioterapia. Colegio Oficial de Fisioterapeutas de La Rioja. Marzo de 2024